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R-410A vs R-22

R-410A

Safety: A1
GWP: 2088
ODP: 0
Category: HFC Blend

R-22

Safety: A1
GWP: 1810
ODP: 0.055
Category: HCFC

Key Differences

R-410A runs about 60–65% higher pressure than R-22 at the same saturation temperature, so R-22 components, gauges and hoses are not rated for it. The two also use different oils (POE vs mineral), so an R-22 system can never be topped up or converted with R-410A.

Pressure at common saturation temperatures:

Pressure Comparison Graph

Side-by-Side Pressures (PSIG)

Temp R-410A R-22 Δ PSIG
-80°F-6.5-9.9-3.4
-75°F-5.1-9.1-4.0
-70°F-3.5-8.1-4.6
-65°F-1.7-7.1-5.4
-60°F0.2-5.9-6.1
-55°F2.5-4.5-7.0
-50°F5.0-3.0-8.0
-45°F7.7-1.3-9.0
-40°F10.80.6-10.2
-35°F14.12.6-11.5
-30°F17.84.9-12.9
-25°F21.97.4-14.5
-20°F26.310.2-16.1
-15°F31.213.2-18.0
-10°F36.516.5-20.0
-5°F42.220.1-22.1
0°F48.424.0-24.4
5°F55.228.3-26.9
10°F62.432.8-29.6
15°F70.337.8-32.5
20°F78.743.1-35.6
25°F87.748.8-38.9
30°F97.455.0-42.4
35°F107.761.5-46.2
40°F118.868.6-50.2
45°F130.676.1-54.5
50°F143.184.1-59.0
55°F156.592.6-63.9
60°F170.7101.6-69.1
65°F185.8111.2-74.6
70°F201.7121.4-80.3
75°F218.6132.2-86.4
80°F236.5143.6-92.9
85°F255.4155.7-99.7
90°F275.3168.4-106.9
95°F296.4181.8-114.6
100°F318.5195.9-122.6
105°F341.9210.8-131.1
110°F366.5226.4-140.1
115°F392.3242.8-149.5
120°F419.5260.0-159.5
125°F448.0278.0-170.0
130°F478.0296.9-181.1
135°F509.5316.7-192.8
140°F542.6337.4-205.2
145°F577.4359.0-218.4
150°F613.9381.7-232.2
155°F652.3405.3-247.0

Frequently Asked Questions

How much higher pressure does R-410A have compared to R-22?

At 70°F, R-410A = 201.7 PSIG vs R-22 = 121.4 PSIG — R-410A runs at about 66% higher pressure. At 130°F head pressure, R-410A = 478.0 PSIG vs R-22 = 296.9 PSIG. This is why R-22 and R-410A equipment are not interchangeable.

Why did R-410A replace R-22?

R-22 is an HCFC that depletes the ozone layer. Under the Montreal Protocol, R-22 production was phased out, banned entirely in the US in 2020. R-410A (an HFC) has zero ozone depletion potential. However, R-410A has a high GWP (2088), and is itself being replaced by R-454B for new equipment.